Sarah A Gagliano Taliun

Thème (s)

• Génomique computationnelle : identification des liens génétiques entre les systèmes cardiovasculaires et neurologiques en utilisant les méthodes computationnelles et bio-informatiques à la fine pointe de la technologie;
• Maladies neurodégénératives : comprendre la contribution de variation génétique;
• Apprentissage automatique : prédiction du risque de développer une maladie complexe.

Publications choisies

• Y. Zhao, S.A. Gagliano Taliun (2022) Lipid-lowering drug targets and Parkinson’s disease: a sex-specific Mendelian randomization study. Frontiers in Neurology. 3:940118. PMID: 36119674.
• T.N. Kelly*, X. Sun*, K.Y. Ye*, M.R. Brown*, S.A. Gagliano Taliun*, J.N. Hellwge*, X. Mi*, J.A. Brody*, […] T.L. Edwards, G.R. Abecasis, X. Zhu, D. Levy, D.K. Arnett, A.C. Morrison. (2022) Insights from a Large-Scale Whole Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension. Hypertension. PMID: 35652341  (*co-premier(ière) auteur/autrice).
• S.A. Gagliano Taliun, P. Sulem, G. Sveinbjornsson, D.F. Gudbjartsson, K. Stefansson, A.D. Paterson, M. Barua. (2022) GWAS of hematuria. Clinical Journal of the American Society of Nephrology. 17(5):672-683. PMID: 35474271.
• S.A. Gagliano Taliun & D.M. Evans. (2021) Ten simple rules for conducting a Mendelian randomization study. PLoS Computational Biology. 17(8): e1009238. PMID: 34383747.
• D Taliun*, DN Harris*, MD Kessler*, J Carlson*, ZA Szpiech*, R Torres*, SA Gagliano Taliun*, A Corvelo*, […] CC Laurie, CE Jaquish, RD Hernandez, TD O’Connor, GR Abecasis. (2021) Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 590:290-299. PMID: 33568819  (*co-premier(ière) auteurs/autrices).
• SA Gagliano Taliun, P VandeHaar, A.P. Boughton, R.P. Welch, D. Taliun, E.M. Schmidt, W. Zhou, J.B. Nielsen, CJ Willer, S Lee, LG Fritsche, M Boehnke, GR Abecasis (2020) Exploring and visualizing large-scale genetic associations using PheWeb. Nature Genetics. 52:550–552. PMID: 32504056.
• RH Reynolds, J Hardy, M Ryten, SA Gagliano Taliun (2019) Informing disease modelling with brain-relevant functional genomic annotations. Brain. 0:1-19. PMID: 31603214.
• RH Reynolds, JA Botía, MA Nalls, International Parkinson’s Disease Genomics Consortium (IPDGC), J. Hardy, SA Gagliano Taliun, M Ryten (2019) Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability. 5:6. NPJ Parkinsons Disease. PMID: 31016231.